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Tag antibodies

Health

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

In a recent study published in Nature Machine Intelligence, a team of researchers used a deep antibody-antigen interaction (DeepAAI) algorithm to understand the antibody representations of unseen antibodies to accelerate the discovery of novel antibodies with potential therapeutic applications. Study:…

GT
November 9, 2022

Health

Higher dose of pneumococcal vaccine improves antibody response in patients receiving rituximab for ANCA-associated vasculitis

New research presented this week at ACR Convergence 2022, the American College of Rheumatology’s annual meeting, showed that a higher dose of pneumococcal vaccine safely and effectively improved antibody response in patients receiving rituximab for ANCA-associated vasculitis (Abstract #L16). Anti-neutrophil…

GT
November 9, 2022

Health

Hybrid immunity from vaccination and Omicron BA.1 or BA.5 breakthrough infections exhibits cross-reactive efficacy against BA.2.75

In a recent study published in Eurosurveillance, researchers from Israel measured the neutralizing antibody titers against the wild-type strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the SARS-CoV-2 Omicron subvariants BA.1, BA.2, BA.2.75 and BA.5 in healthcare workers…

GT
November 8, 2022

Health

Evaluating dual direct-acting antivirals against persistent COVID-19

In a recent study posted to the Research Square* preprint server, researchers assessed the efficiency of dual direct-acting antivirals in treating persistent coronavirus disease 2019 (COVID-19). Study: Severe COVID-19 caused by persistent SARS-CoV-2 infection successfully treated with dual direct acting…

GT
November 7, 2022

Health

Study finds no evidence of major SARS-CoV-2 spread among wild rodents

Previous research has indicated the reverse transmission of various zoonotic pathogens from humans to animals as a global concern. Furthermore, the World Organisation for Animal Health (OIE) on 6th July 2022 stated that while occasional occurrences of COVID-19 in domestic…

GT
November 7, 2022

Health

Researchers identify therapies for multiple myeloma patients whose cancer relapses after CAR-T

Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an immunotherapy known as CAR-T only to find their cancer coming back afterwards. CAR-T, short…

GT
November 4, 2022

Health

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Monkeypox has infected more than 77,000 people in more than 100 countries worldwide, and -; similar to COVID-19 -; mutations have enabled the virus to grow stronger and smarter, evading antiviral drugs and vaccines in its mission to infect more…

GT
November 4, 2022

Health

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

In a recent study published in Cell Reports, researchers generated and characterized two monoclonal antibodies (NA8 and NE12) that target the receptor binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and exhibit neutralizing activity against…

GT
November 3, 2022

Health

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

The world has recently seen immense activity in the field of vaccine development due to the coronavirus disease 2019 (COVID-19) pandemic, as the causative virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to emerge in new variants with…

GT
November 2, 2022

Health

How does imprinted SARS-CoV-2 humoral immunity drive convergent Omicron evolution?

In a recent study posted to the bioRxiv* server, researchers examined how imprinted severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) humoral immunity drives convergent evolution in continuously emerging Omicron subvariants. Notably, they investigated the humoral immune imprinting response only in recipients…

GT
November 2, 2022

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