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In a recent study posted to the bioRxiv* preprint server, researchers assessed the de novo and recall T cell responses during coronavirus disease 2019 (COVID-19) breakthrough infection. Study: Rapid recall and de novo T cell responses during SARS-CoV-2 breakthrough infection.…
A recent study posted to the bioRxiv* preprint server described the cell-free manufacturing of griffithsin (GRFT), a broad-spectrum antiviral protein. Study: An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics. Image Credit:…
Lung cancer is the deadliest cancer in the United States and around the world. Many of the currently available therapies have been ineffective, leaving patients with very few options. A promising new strategy to treat cancer has been bacterial therapy,…
If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities. Formed in response to infection and vaccination, these microscopic training…
In a recent study published in Science, researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C). Study: Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory…
In a recent study published in eBioMedicine, researchers evaluated plasma and nasal antibody titers responses induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccinations among United Kingdom (UK) residents. Study: SARS-CoV-2-specific nasal…
People with hematologic malignancies are at greater risk of severe coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, studies exploring the immune response to the COVID-19 vaccine have been scarce. A recent Nature Cancer…
Inflammation and overactivation of the immune system in the brain can cause loss of synapses and the death of neurons, leading to neurodegenerative and psychiatric diseases. In Schizophrenia, increased levels of the immune protein C4 have been measured in patients’…
A team of China-based scientists has recently estimated and compared the levels of anti-mpox and anti-vaccinia antibodies in gay men and the general population. The study is currently available on the medRxiv* preprint server. Study: Unexpectedly higher levels of naturally…
In a recent study posted to the bioRxiv* preprint server, researchers report that sublineages of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant effectively escape B-cell immune responses by modifying neutralizing antibody epitopes. Comparatively, T-cell immunity, which primarily targets the…
