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ABO blood-type compatibility between organ donors and recipients is crucial for safe transplantations. Across the different ABO blood groups, longer wait-times for a kidney transplant are often experienced by patients who have type B blood because it is a less…
In a recent article published in Scientific Reports, researchers performed an observational study among coronavirus disease 2019 (COVID-19) patients and their close contacts registered with the Bangkok home health care services in Thailand. They assessed their T-cell and neutralizing antibody…
Cells jostling for a spot in a germinal center face a cutthroat admissions process. Formed after exposure to a pathogen or vaccine, germinal centers act as a kind of immune system training academy, helping B cells refine their response to…
In a recent article published in the Lancet Microbe, researchers in the Netherlands and the United Kingdom quantified the antigenic diversity of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subvariants, BQ.1.1, BM.1.1.1, and XBB.1, all derivatives of the variant…
In a recent study posted to the medRxiv* preprint server, researchers assessed the efficacy of the coronavirus disease 2019 (COVID-19) second booster vaccine compared to the first booster vaccine and the protection conferred by prior COVID-19 infection. Study: Effectiveness of…
In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom developed a pooled enzyme-linked immunosorbent (ELISA) assay using mpox (MPX) virus (MPXV) antigens and vaccinia virus (VACV) antigens. They also assessed humoral responses to and…
In a recent study posted to the medRxiv* preprint server, researchers explored the effects of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination on SARS-CoV-2 Omicron infection. Study: The effect of previous SARS-CoV-2 infection and COVID-19 vaccination…
Using new microscopic methods in combination with machine learning-based image analysis, researchers from Freiburg have discovered new structures on the surface of living B cells that affect the distribution and possibly the function of their antigen receptors. The researchers’ study…
For men with early-stage prostate cancer being managed by active surveillance, adding the hormonal agent apalutamide may lower the rate of positive biopsies during follow-up, suggests a preliminary clinical trial in The Journal of Urology®, an Official Journal of the…
In a recent study posted to the bioRxiv* preprint server, researchers at Columbia University characterized reciprocal and non-reciprocal T-cell responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). T-cell immunity is essential for positive clinical outcomes of SARS-CoV-2 infection. Hence,…
