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In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom developed a pooled enzyme-linked immunosorbent (ELISA) assay using mpox (MPX) virus (MPXV) antigens and vaccinia virus (VACV) antigens. They also assessed humoral responses to and…
In a recent study posted to the medRxiv* preprint server, researchers explored the effects of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination on SARS-CoV-2 Omicron infection. Study: The effect of previous SARS-CoV-2 infection and COVID-19 vaccination…
Using new microscopic methods in combination with machine learning-based image analysis, researchers from Freiburg have discovered new structures on the surface of living B cells that affect the distribution and possibly the function of their antigen receptors. The researchers’ study…
For men with early-stage prostate cancer being managed by active surveillance, adding the hormonal agent apalutamide may lower the rate of positive biopsies during follow-up, suggests a preliminary clinical trial in The Journal of Urology®, an Official Journal of the…
In a recent study posted to the bioRxiv* preprint server, researchers at Columbia University characterized reciprocal and non-reciprocal T-cell responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). T-cell immunity is essential for positive clinical outcomes of SARS-CoV-2 infection. Hence,…
In a recent study posted to bioRxiv*, researchers designed a nanoparticle (NP)-conjugated toll-like receptor 9 (TLR9) agonist to improve the adjuvanticity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. Subunit vaccines contain protein antigens and one or more adjuvants,…
In a recent study posted to the medRxiv* preprint server, researchers at Oregon Health & Science University assessed the impact of the duration between coronavirus disease 2019 (COVID-19) infection and vaccination on immunity against infection. As the spread of severe…
There has been an increase in the development of coronavirus disease 2019 (COVID-19) vaccines in several countries due to the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The RNA vaccine platform is a next-generation platform that comprises…
In a recent article published in Science Translational Medicine, researchers developed a novel pan-vaccine antigen (Span)-based subunit vaccine against coronavirus disease 2019 (COVID-19). Using a mouse model, they also demonstrated that this vaccine formulation conferred protection against multiple clades of…
This new article publication from Acta Pharmaceutica Sinica B, discusses a fully synthetic Tn-based three-component cancer vaccine using covalently linked TLR4 ligand MPLA and iNKT cell agonist KRN-7000 as built-in adjuvant effectively protects mice from tumor development. The authors of…
