Physical Address
304 North Cardinal St.
Dorchester Center, MA 02124
Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumors sensitive to a type of immunotherapy drug called a checkpoint inhibitor. This is according to a new study published in Cancer…
In a recent study published in the journal PLOS Pathogens, researchers investigated the mechanisms through which the human common cold Betacoronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit the formation of stress granules. Study: Nsp1 proteins…
In a recent study posted to the medRxiv* preprint server, researchers from Germany conducted a population-based surveillance study to ascertain the etiology of community-acquired pneumonia (CAP) during the re-emergence of viral and bacterial respiratory diseases after the relaxation of coronavirus…
In a recent study posted to the Research Square* preprint server, researchers reported the waning of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the six months following a booster dose of the messenger ribonucleic acid (mRNA) coronavirus…
In two separate studies, researchers demonstrate how synthetic biology can be used to tackle a difficult issue in cancer immunotherapy: the way immunotherapy-related approaches focused on short-term killing of tumor cells may fail to eradicate tumors because growth of tumors…
In a recent study published in Immunity, researchers isolated SARS-CoV-2 spike (S) protein-targeted mAbs (monoclonal antibodies) from convalescent healthcare workers (HCWs), emphasizing the IGHV1-69 (immunoglobulin heavy variable 1-69) gene, the gene with the greatest structural and allelic variation. Study: Immunoglobulin…
In a recent study posted to the medRxiv* preprint server, researchers assessed the immunogenicity of a variant-adapted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recombinant protein vaccine boosted with an AS03 adjuvant. Study: Safety and immunogenicity of a variant-adapted SARS-CoV-2…
A recent study published in Alimentary Pharmacology and Therapeutics reports that patients with a lower hepatitis B virus (HBV) haplotype number of less than or equal to two are more likely to achieve a functional cure with chronic hepatitis B treatment. Study: Hepatitis…
In this special supplement to the Journal of Parkinson’s Disease, “The Immune System in Parkinson’s Disease,” experts highlight the latest research breakthroughs on the links between immune activation and neuroinflammation and Parkinson’s disease (PD) and discuss the challenges and novel…
In a recent study posted to the bioRxiv* server, researchers mutated the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein’s trimeric structure to design a novel prefusion S antigen, S2D14. Study: Structural and Computational Design of a SARS-2…
