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The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration. This month’s featured article, “A high-throughput MALDI-TOF MS biochemical…
Bacteria of the genus Enterobacter are among the most dangerous bacteria associated with hospital infections worldwide. Some of their representatives are highly resistant to commonly used antibiotics, so that the reserve antibiotic colistin is increasingly used as a last resort…
In a recent study published in eClinicalMedicine, researchers conducted a serosurvey during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron wave in Malawi. Study: Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high…
A study conducted in Brazil and reported in an article published in Molecular Psychiatry suggests that schizophrenia may be associated with alterations in the vascularization of certain brain regions. Researchers at the State University of Campinas (UNICAMP), D’Or Research and…
ABO blood-type compatibility between organ donors and recipients is crucial for safe transplantations. Across the different ABO blood groups, longer wait-times for a kidney transplant are often experienced by patients who have type B blood because it is a less…
Mice exposed to World Trade Center dust exhibit a significant impairment in spatial recognition and short- and long-term memory, as well as changes in genes related to immune-inflammatory responses and blood-brain barrier disruption, according to a study conducted by researchers…
In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom developed a pooled enzyme-linked immunosorbent (ELISA) assay using mpox (MPX) virus (MPXV) antigens and vaccinia virus (VACV) antigens. They also assessed humoral responses to and…
In a recent study posted to the bioRxiv* preprint server, researchers explored the effects of mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) on viral transmission. Study: The effect of previous SARS-CoV-2 infection and…
In a recent study posted to the bioRxiv* preprint server, researchers discovered that the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is susceptible to cleavage at the disulfide bonds. They also found that the vulnerability to reductive…
In a recent study posted to the bioRxiv* preprint server, researchers at Emory University used severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Washington (WA.1) and Omicron (BA.1) strains to test for mutations that could result in resistance to the antiviral…
