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Inhibition of the ERK5 protein kinase reduces the proliferation and survival of endometrial cancer cells, and potentiates standard chemotherapy. Endometrial cancer is the most common type of gynecological cancer and is the fourth most common type of tumor in women…
In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment. Their target is SAMHD1, a protein which can protect us from viral infections by destroying an…
Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs. The discovery, published in the October 26, 2022 issue of Nature, opens…
Heme, the iron-holding molecule that gives blood its red color, is essential for life. Yet, ironically, it can be quite toxic if not properly handled. In fact, numerous diseases – from various cancers to cardiovascular diseases – are associated with…
Throughout the ongoing coronavirus disease 2019 (COVID-19) pandemic, which has been caused by the spread of the highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), scientists have developed various innovative diagnostic tools, many of which have been extended beyond…
Many diseases have at their origin a protein that does not function properly. Now, a multidisciplinary research team with Texas A&M AgriLife and Texas A&M University has found a way to deliver a protein quickly, effectively and briefly to the…
On 6th September 2022, the Azerbaijan Thalassemia Center and BGI held a virtual signing ceremony to seal a Collaboration Agreement. The partnership aims to improve thalassemia screening in Azerbaijan through genetic technology. In early 2021, in occasion of the “Prevention…
The availability of rapid antigen tests has significantly advanced efforts to contain the spread of COVID-19, but every new variant of concern raises questions about whether diagnostic tests will still be effective. A new study published in Cell attempts to…
Mitochondria are remarkable shape-shifting organelles that have long been understood as the powerhouses inside our cells. But relatively little is known about how the constant fission and fusion of these tiny energy generators impacts stem cell function and tissue regeneration.…
Alzheimer’s disease (AD) is the most common type of dementia affecting an estimated 6.3 million Americans age 65 and older. Without the development of medical breakthroughs to prevent, treat, slow or cure AD that number could grow to 13.8 million…
