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Many cardiovascular diseases, such as atherosclerosis, or ‘hardening of the arteries,’ correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant improvement in therapies to treat cardiovascular disease, there is an…
Pulmonary arterial hypertension (PAH) is a rare and incurable disease of the lung arteries that causes early death. In PAH, excess scar tissue and thickening of lung blood vessels occur as the result of increased cell “biomass.” These changes obstruct…
A study conducted in Brazil and reported in an article published in Molecular Psychiatry suggests that schizophrenia may be associated with alterations in the vascularization of certain brain regions. Researchers at the State University of Campinas (UNICAMP), D’Or Research and…
Pipes play an essential role in bringing water to the faucets in your home, but if one of those pipes springs a leak, damage can result. Similarly, the vascular system plays an essential role in carrying oxygen and nutrients throughout…
Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) -; the most common form of the chronic autoimmune disease lupus. A multidisciplinary team of investigators at Vanderbilt University Medical Center has…
A recent study published in the journal Nature reported the co-aggregation of medin, a fragment of lactadherin, with vascular amyloid-β in Alzheimer’s disease (AD). Amyloidosis is caused by systemic or local accumulation of misfolded, insoluble, and aggregated proteins. So far,…
A Rutgers analysis of U.S. stroke deaths from 1975 to 2019 has found both a dramatic decline and the potential for an important resurgence. Stroke mortality (per 100,0000) plummeted from 88 to 31 for women and 112 to 39 for…
In a new study involving three volunteers, skin scars began to behave more like uninjured skin after they were treated with hair follicle transplants. The scarred skin harbored new cells and blood vessels, remodeled collagen to restore healthy patterns, and…
Researchers at the University of Bristol funded by the British Heart Foundation (BHF) have developed ‘stem cell plasters’ to revolutionize the way surgeons treat children living with congenital heart disease, so they don’t need as many open-heart operations. Heart defects…
A serious condition that can cause the kidneys to suddenly stop working could be treated with existing medicines, a new study shows. In a study in mice scientists found that medicines usually used to treat angina and high blood pressure…
