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Researchers at the Josep Carreras Leukaemia Research Institute have developed a method to analyze long-range interactions in the DNA -the interactome- from a very low amount of starting material. The method, named liCHi-C, opens the door to study the interactome…
Research suggests that the risk of dying from any type of cancer is 18 per cent higher among people with type 2 diabetes, compared with the general population Health 24 January 2023 By Sara Novak Type 2 diabetes, which requires…
In a recent study published in Cell, researchers used multiplexed and three-dimensional imaging with machine-based learning and spatial statistics to perform molecular and morphological assessments of colorectal cancers (CRC). Study: Multiplexed 3D atlas of state transitions and immune interaction in…
It’s a good news, bad news story. Patients whose brain tumors have a mutated enzyme called IDH1 typically live longer than those without the mutation. But even as these tumors are initially less aggressive, they always come back. A key…
Many cardiovascular diseases, such as atherosclerosis, or ‘hardening of the arteries,’ correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant improvement in therapies to treat cardiovascular disease, there is an…
Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work – until now. In a paper published in the journal Nature Biotechnology, University of Cambridge researchers…
Immunotherapies have improved outcomes of many patients with cancer, including melanoma. But these therapies work for only a subset of patients. Numerous studies are looking at improving responses, including research focusing on enhancing tumor-infiltrating lymphocytes (TILs). TILs are immune cells…
A four-drug chemotherapy regimen provided longer overall survival than a two-drug combination in a Phase 3 clinical trial for metastatic pancreatic ductal adenocarcinoma. The study is believed to be the first metastatic pancreatic cancer study in nearly a decade to…
UK patients will benefit from a new partnership with Thailand to share expertise of genome sequencing, collaborate in research, education and training opportunities, knowledge exchange and genomics data handling. Yesterday afternoon (Thursday 19 January) the Memorandum of Understanding was signed…
In this interview, News-Medical speaks to Dr. Jeremy Carlton and Professor Victoria Sanz-Moreno about their latest research into the spread of skin cancer. Please can you introduce yourself and tell us about your professional background? Carlton: I’m a Wellcome Trust…
