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The Omicron variant of concern (VOC) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly, displacing earlier variants worldwide. It caused large numbers of breakthrough infections even in those people who had hybrid immunity (“generated through a combination…
In a recent article published in Emerging Infectious Diseases, researchers examined a prospective cohort of frontline workers in the United States (US) previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They attempted to identify risk factors that made this…
A recent study posted to the medRxiv* preprint server suggests that repeated vaccination at frequent intervals might improve coronavirus disease 2019 (COVID-19) vaccine efficacy and the trajectory of the pandemic. Study: The impact of vaccination frequency on COVID-19 public health outcomes: A…
In a recent study posted to medRxiv* preprint server, researchers examined the associations between coronavirus disease 2019 (COVID-19) and incident autoimmune diseases. Study: Incident autoimmune diseases in association with a SARS-CoV-2 infection: A matched cohort study. Image Credit: Kateryna Kon/Shutterstock…
A recent study posted to medRxiv* preprint server reported a novel form of post-acute coronavirus disease 2019 (COVID-19) syndrome in children. Study: Acute tubulointerstitial nephritis with or without uveitis: a novel form of post-acute COVID-19 syndrome in children. Image Credit:…
In a recent study posted to the bioRxiv* preprint server, researchers investigated whether endothelial TLR3 (toll-like receptor 3) insufficiency contributes to lung vascular remodeling induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: A role for Toll-like receptor 3…
In a recent study posted to the bioRxiv* preprint server, researchers characterized immunological responses by pulmonary mucosal tissues post-coronavirus disease 2019 (COVID-19) vaccination and/or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, to assess the impact of hybrid immune protection…
A recent report by the American Heart Association published in the journal Circulation reported the updated statistics on the major circulatory and cardiovascular diseases, and their outcomes for 2023, with additional insights into the trends in heart disease during the…
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, causes respiratory infection in people of all ages. Compared to adults, children are less frequently and severely affected by SARS-CoV-2. Although the…
The enzyme 3-chymotrypsin-like cysteine protease (3CLpro) is a key drug target for the treatment of the coronavirus disease 2019 (COVID-19). Moreover, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro is essential throughout the viral life cycle and exhibits high…
