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How much do genes influence our body weight? For the general population this influence is around 20%, according to studies that in recent years have analyzed the complete genome of tens of thousands of people. In other words, “lifestyle, such…
Scientists have discovered the cause of a rare condition within a part of the genome that has been largely unexplored in medical genetics. A team at the University of Exeter has found genetic changes in a region that controls the…
An international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expression is tightly correlated with response to chemotherapy in medulloblastomas, a highly malignant brain tumor affecting pediatric, adolescent, and young…
In a recent study published in Viruses, researchers used whole genome sequencing to evaluate monkeypox virus samples from Washington and Ohio in the United States and identified 25 samples with open reading frame (ORF)-disrupting mutations. Study: ORF-Interrupting Mutations in Monkeypox…
In a recent study posted to the medRxiv* preprint server, researchers investigated whether the time of day at which coronavirus disease 2019 (COVID-19) patients receive their severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations influences the vaccine effectiveness (VE). Study:…
In a recent study posted to the bioRxiv* preprint server, researchers evaluated the efficacy of four doses of parental messenger ribonucleic acid (mRNA) vaccine and a BA.5-bivalent booster against recently emerged Omicron sublineages. Additionally, they determined whether prior infection improved…
In a recent study published in the journal Free Radical Biology and Medicine, researchers screened for neuroprotective compounds against Alzheimer’s disease (AD). Alzheimer’s disease, the sixth leading cause of death in the United States (US), is a progressive neurodegenerative condition…
Scientists at the UNC School of Medicine and UNC Eshelman School of Pharmacy, in collaboration with a team from Queen Mary University of London, have illuminated the molecular events underlying an inherited movement and neurodegenerative disorder known as ARSACS –…
Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain…
In a recent study posted to medRxiv* preprint server, researchers characterized trends of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA levels in wastewater. Study: Identifying trends in SARS-CoV-2 RNA in wastewater to infer changing COVID-19 incidence: Effect of sampling…
