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In patients with Huntington’s disease, neurons in a part of the brain called the striatum are among the hardest-hit. Degeneration of these neurons contributes to patients’ loss of motor control, which is one of the major hallmarks of the disease.…
Editing a gene that prompts a cascade of damage after a heart attack appeared to reverse this inevitable course in mice, leaving their hearts remarkably unharmed, a new study by UT Southwestern scientists showed. The findings, published in Science, could…
Circadian rhythms are inherent cycles of approximately 24 hours that regulate various biological processes, such as sleep and wakefulness. A research group at Nagoya University in Japan has recently revealed that neural networks play an important role in the regulation…
In a recent study posted to the bioRxiv* preprint server, researchers performed age-reversing experiments, in vivo and in vitro, in progeroid mice using gene therapy. Study: Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice.…
Raphidocystis contractilis belongs to Heliozoa, a group of eukaryotes commonly found in fresh, brackish, and sea water. The organisms of this group have finger-like arms-;axopodia-;which radiate out from their body, giving them a sun-like appearance. Hence, they are also known…
Aging involves a balance between oxidants and antioxidants, low-grade inflammation and a protein response that occurs at the cellular level, which is responsible for many health disorders. Exercise has been shown to regulate the inflammatory response, balance oxidants such as…
Hormone Replacement Therapy (HRT) could help prevent Alzheimer’s Dementia among women at risk of developing the disease – according to University of East Anglia research. The study shows that HRT use is associated with better memory, cognition and larger brain…
A new research paper was published in Genes & Cancer on December 14, 2022, entitled, “Slit2 signaling stimulates Ewing sarcoma growth.” Ewing sarcoma is a cancer of bone and soft tissue in children driven by EWS::ETS fusion, most commonly EWS::FLI1.…
When genes are activated and expressed, they show patterns in cells that are similar in type and function across tissues and organs. Discovering these patterns improves our understanding of cells -; which has implications for unveiling disease mechanisms. The advent…
In a recent study posted to the bioRxiv* preprint server, researchers evaluated the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the peripheral nervous system (PNS). Study: Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2 strain…
