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Around 10% of the global population is affected by chronic kidney disease (CKD). The risk of CKD progressing into end-stage renal disease (ESRD) is exceptionally high, which requires dialysis or kidney transplantation. At present, there is no effective treatment for…
In a recent study published in the Cell, researchers assessed the role of angiotensin-converting enzyme 2 (ACE2) in the coronavirus disease 2019 (COVID-19) pandemic. Study: Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemic. Image Credit: Kateryna Kon/Shutterstock Background ACE2…
A recent study published in the journal Trends in Endocrinology and Metabolism discusses recent findings linking satiety to the gut microbiome. Study: Influence of the gut microbiota on satiety signaling. Image Credit: FOTOKITA / Shutterstock.com The microbiome and metabolism A growing body…
Glioblastoma is a malignant tumor of the central nervous system (brain or spinal cord) and one of the deadliest types of cancer. Few drugs have proved effective at combating this uncontrolled growth of glial cells, which anyway constitute a large…
CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single-and multi-organ microphysiological systems (MPS), today announced the commercial launch of the PhysioMimix™ Single-organ Higher Throughput (HT) System. The Company’s first HT system has been designed to overcome adoption…
Different cell types-;say, heart, liver, blood, and sperm cells-;possess characteristics that help them carry out their unique jobs in the body. In general, those characteristics are hard-wired. Without intervention, a heart cell won’t spontaneously transform into a liver cell. Yet…
Despite the fact that we all start out as an egg cell in one of our mother’s ovaries, these human reproductive organs are surprisingly under-studied. Scientists have been working on creating in vitro models of human ovaries so that we…
*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. In a recent study posted to the bioRxiv* server, researchers used a…
To commemorate World Cancer Day, we spoke to a multidisciplinary team of researchers from The Institute of Cancer Therapeutics (ICT) based at the University of Bradford about their work in cancer research. Please can you introduce yourself and tell us…
In a recent study published in Science Immunology, researchers investigated the CAMCI (combination of cell activation and metabolic checkpoint inhibition) strategy as an immunotherapeutic option for inflammatory bowel disease (IDB). Study: CD4+ T cell activation and concomitant mTOR metabolic inhibition…
