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Researchers from the Icahn School of Medicine at Mount Sinai have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses. This research opens the door to studying how…
Different cell types-;say, heart, liver, blood, and sperm cells-;possess characteristics that help them carry out their unique jobs in the body. In general, those characteristics are hard-wired. Without intervention, a heart cell won’t spontaneously transform into a liver cell. Yet…
In a recent study posted to the bioRxiv* preprint server, researchers evaluated the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the peripheral nervous system (PNS). Study: Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2 strain…
A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals’ cortex and responded to external sensory stimuli. The implanted organoids reacted to visual stimuli…
Although Michelangelo’s masterpiece David captured the magnificence of the human body – how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century. This has been largely due to technical limitations and…
In a recent study posted to the bioRxiv* preprint server, researchers developed a three-dimensional (3D) in vitro tissue model to assess the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the vascular endothelial cells. Study: SARS-CoV-2 spike protein…
Bats have evolved with unique features such as laryngeal echolocation and flight, with some capable of tolerating viruses such as severe acute respiratory syndrome coronaviruses (SARS-CoVs), Middle East respiratory syndrome CoVs (MERS-CoVs), as well as Marburg and Nipah viruses. Developing…
