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Parkinson’s disease (PD) is an incurable neurodegenerative disease that affects one in a hundred people the world over, second only to Alzheimer’s disease in the number of people affected. However, the mechanism by which it arises is still unclear. In…
Tyrosine kinase inhibitors are a type of targeted cancer medicine that can attack specific types of cancer cells and prevent them from multiplying. Although these inhibitors, called TKIs, can be very useful in fighting certain cancers, they also cause serious…
A new approach that delivers a “one-two punch” to help T cells attack solid tumors is the focus of a preclinical study by researchers from the Perelman School of Medicine at the University of Pennsylvania. The findings, published in the…
New research from the University of Missouri School of Medicine has established a link between western diets high in fat and sugar and the development of non-alcoholic fatty liver disease, the leading cause of chronic liver disease. The research, based…
In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus. Study: Is human obesity an inflammatory disease of the hypothalamus? Image Credit: SciePro / Shutterstock Background…
*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. While the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the influenza…
Having both diabetes and tooth loss contributes to worse cognitive function and faster cognitive decline in older adults, according to a new study published in a special issue of the Journal of Dental Research focused on aging and oral health.…
In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the impact of an anti-CD3 monoclonal antibody (mAb) called Foralumab in coronavirus disease 2019 (COVID-19) treatment. Study: Nasal administration of anti-CD3 mAb (Foralumab) downregulates…
A study published in Scientific Reports highlights that gout can increase the risk of Alzheimer’s disease and Parkinson’s disease in younger or overweight individuals. The study was conducted in a representative Korean population. Study: Longitudinal follow-up study of the association…
Atherothrombosis is a progressive disease caused by mineral, lipid, and fibrous deposits in arterial walls. This accumulation leads to the narrowing of the arterial lumen. In addition, Hyperlipidaemia and inflammation enhance the risk of future atherothrombotic events, even in people…