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Energy production in nature is the responsibility of chloroplasts and mitochondria and is crucial for fabricating sustainable, synthetic cells in the lab. Mitochondria are not only “the powerhouses of the cell,” as the middle school biology adage goes, but also…
After more than two years since its discovery, six million deaths, and half a billion reported cases, there is still no effective cure for COVID-19. Even though vaccines have lowered the impact of outbreaks, patients that contract the disease can…
In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the capability of two small molecules of disintegrating alpha-synuclein fibrils. Study: Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils. Image Credit:…
Circadian rhythms are inherent cycles of approximately 24 hours that regulate various biological processes, such as sleep and wakefulness. A research group at Nagoya University in Japan has recently revealed that neural networks play an important role in the regulation…
While many studies have examined male salt consumption behaviors, less research has examined how these behaviors may differ among female subjects. To this end, a recent Nutrients journal study reviews differences in salt intake based on sex. Study: Sex differences in…
In a recent study posted to bioRxiv*, researchers designed a nanoparticle (NP)-conjugated toll-like receptor 9 (TLR9) agonist to improve the adjuvanticity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. Subunit vaccines contain protein antigens and one or more adjuvants,…
Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies. Therefore, these methodologies often fail when applied in a clinical environment with patients. In this context, the findings…
A fundamental challenge in drug development is the balance between optimizing a drug’s lock-and-key fit with its target and the drug’s ability to make its way across the cellular membrane and access that target. The search for cell-permeable drugs has…
On 11th March 2020, the World Health Organization (WHO) announced the global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the coronavirus disease 2019 (COVID-19). Despite the discovery of effective COVID-19 vaccines and the subsequent commencement of…
In a recent article published in the journal Cell, researchers found fungal deoxyribonucleic acid (DNA) and cells at low abundances across many human cancers, with cancer type-dependent variations in fungus community composition and fungal-bacteriome interactions. Study: Pan-cancer analyses reveal cancer-type-specific…
