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In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by the intestinal microbiome and by sex. Study: Low Gut Microbial Diversity Augments Estrogen-Driven Pulmonary Fibrosis in Female-Predominant Interstitial Lung Disease. Image Credit: Magic mine/Shutterstock…
In a recent study posted to the medRxiv* preprint server, researchers described the second update on the study of human genetic architecture concerning the effect of coronavirus disease 2019 (COVID-19). Study: A second update on mapping the human genetic architecture of…
In a recent study published in Immunity, researchers isolated SARS-CoV-2 spike (S) protein-targeted mAbs (monoclonal antibodies) from convalescent healthcare workers (HCWs), emphasizing the IGHV1-69 (immunoglobulin heavy variable 1-69) gene, the gene with the greatest structural and allelic variation. Study: Immunoglobulin…
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals display a wide range of clinical variations, from asymptomatic infection to lethal disease. In a recent study published on the bioRxiv* preprint server, and international team of researchers investigated the genetic, immunological,…
In a recent study published in the Journal of Allergy and Clinical Immunology, researchers examined the gene-environment (GxE) interactions between pet ownership in infancy and the 17q12-21 (asthma-risk) locus concerning wheezing. Study: Dog ownership in infancy is protective for persistent…
In a recent study posted to bioRxiv*, researchers performed an analysis of molecular variance (AMOVA) in 59 haplotypes of the interferon (IFN)-alpha (α) /beta (β) receptor (IFNAR) gene, departing from monkeypox (MPX) virus (MPXV), camelpox virus, buffalopox virus, ectromelia virus,…
