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*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. A team of scientists from Australia and Israel demonstrates that Candida auris,…
As a chronic pro-inflammatory disease, obesity is closely associated with the development of various diseases such as type 2 diabetes, cardiovascular disease and cancers. Obesity is now a major concern for public health. Macrophages have been known to play an…
In a recent study posted to the bioRxiv* preprint server, researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro. Study: Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe…
Dec 27 2022 UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure. The finding, published in Immunity, could pave the way for developing…
In a recent study posted to the medRxiv* preprint server, researchers investigated the clinical, histopathological, imaging, and serological characteristics of post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) in patients with mild COVID-19. Study: Clinical, imaging, serological, and histopathological features…
A recent study posted to the bioRxiv* preprint server reported that helminth exposure enhances viral clearance and survival of mice challenged with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T…
Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers. Scientists can build them in various shapes with different materials, often as porous, crystal-like structures formed by a lattice…
A new approach to cancer immunotherapy that uses one type of immune cell to kill another-;rather than directly attacking the cancer-; provokes a robust anti-tumor immune response that shrinks ovarian, lung, and pancreatic tumors in preclinical disease models, according to…
Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil suggest that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits SARS-CoV-2 replication as well as the exacerbated inflammatory response that leads to death…
A Ludwig Cancer Research study has developed a strategy to noninvasively track immune cells known as macrophages within brain and breast tumors in living mice. Cancers often recruit and reprogram these tumor-associated macrophages, or TAMs, to support their own growth…
