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Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2. In doing so, they reveal the inner workings of insulin-regulated metabolism. The findings lead the way for Akt2-targeting therapeutics for…
The human gut microbiota yields about 100 trillion microorganisms, involving bacteria, viruses, yeasts, and parasites. At birth, the human gut is mostly sterile and gets colonized by its mother’s microbiome. The type of delivery, cesarean or vaginal, plays an essential…
In a recent study published in Microbiology Spectrum, researchers found that differences in the dietary patterns of children with normal weight and those who were overweight or obese contributed to variations in the gut microbiome diversity, virulence factors of gut…
In a recent review published in Advances in Food and Nutrition Research, researchers assessed the function of lipids in metabolic diseases. Study: We are what we eat: The role of lipids in metabolic diseases. Image Credit: Kateryna Kon/Shutterstock Background Lipids play…
Type 2 diabetes mellitus is a common lifestyle disease that is prevalent worldwide. It can often lead to complications, such as diseases of the heart, and increased risk of death, but preventive measures, such as a healthy diet, can reduce…
In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders. Obesity results from higher energy intake compared to energy expenditure, which…
Ammonium is a biomarker used to diagnose a series of rare hereditary metabolic disorders, such as the primary disorders of the urea cycle and different organic acidemias, as well as other metabolic and environmental conditions affecting the liver’s function, which…
Microbiomes refer to the collective genomes of microorganisms living in a particular environment. The microbiota refers to the community of microbes themselves. For example, the human gastrointestinal tract contains approximately 100 trillion microorganisms (primarily bacteria, but also viruses, fungi, and…
A team led by Van Andel Institute scientists has identified two distinct types of obesity with physiological and molecular differences that may have lifelong consequences for health, disease and response to medication. The findings, published today in the journal Nature…
In a recent study published in the journal Nature, researchers explored the neural basis for fat preference and identified receptors and neuronal elements mediating its development. Study: Gut-Brain Circuits for Fat Preference. Image Credit: Pikovit / Shutterstock Background The current global obesity…
