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A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found. The results of the “hit and run” drug delivery system, published in the March issue of…
New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread,…
*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. In a recent study posted to the bioRxiv* preprint server, researchers examined…
In a recent report published in Vaccine, researchers presented the coronavirus vaccines research and development roadmap (CVR) to promote the development of broadly protective coronavirus disease 2019 (COVID-19) vaccines. Study: A Research and Development (R&D) Roadmap for Broadly Protective Coronavirus…
In a recent study posted to the bioRxiv* preprint server, researchers from the United States evaluated the efficacy and immunogenicity of an intranasal messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using a…
In a recent study posted to bioRxiv*, researchers designed a nanoparticle (NP)-conjugated toll-like receptor 9 (TLR9) agonist to improve the adjuvanticity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. Subunit vaccines contain protein antigens and one or more adjuvants,…
Using a specialized MRI sensor, MIT researchers have shown that they can detect light deep within tissues such as the brain. Imaging light in deep tissues is extremely difficult because as light travels into tissue, much of it is either…
In a recent review published in Nature Nanotechnology, researchers provided an overview of nanomedicine strategies to treat coronavirus disease 2019 (COVID-19)-induced thrombosis. Study: The potential impact of nanomedicine on COVID-19-induced thrombosis. Image Credit: MattLphotography/Shutterstock The complex and unique pathophysiology…
Lipid nanoparticle (LNP)-based messenger ribonucleic acid (mRNA) vaccines have recently emerged as a promising strategy for the prevention and treatment of cancers, as well as infectious diseases. LNPs are carriers that safely and effectively deliver nucleic acid vaccines, eliciting a…
November 18th, 2022. Today, Applied Cells Inc. and GenScript USA Incorporated announced their strategic collaboration to deliver combined cell isolation solutions for cell therapy drug development worldwide. Under this collaboration, GenScript will develop and supply its proprietary research and cGMP…