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Parkinson’s disease (PD) is an incurable neurodegenerative disease that affects one in a hundred people the world over, second only to Alzheimer’s disease in the number of people affected. However, the mechanism by which it arises is still unclear. In…
In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer’s disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.…
Glioblastoma is a malignant tumor of the central nervous system (brain or spinal cord) and one of the deadliest types of cancer. Few drugs have proved effective at combating this uncontrolled growth of glial cells, which anyway constitute a large…
In a recent perspective published in Science, researchers explored microfluidic systems with a skin interface in assessing chemical exposure and health status. Study: Sweat as a diagnostic biofluid. Image Credit: CGN089/Shutterstock Background The skin’s eccrine sweat glands are essential elements…
A team from the University of Michigan has developed a new software tool to help researchers across the life sciences more efficiently analyze animal behaviors. The open-source software, LabGym, capitalizes on artificial intelligence to identify, categorize and count defined behaviors…
In a recent study published in Nanomedicine: Nanotechnology, Biology and Medicine, researchers evaluated the biodistribution of cannabidiol (CBD) emulsion and nanoparticles in the central nervous system (CNS). Study: Evaluation of cannabidiol nanoparticles and nanoemulsion biodistribution in the central nervous system…
*Important notice: Research Square publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. Parkinson’s disease (PD) is a neurodegenerative disorder that leads to the…
The so-called isolated REM-sleep behavior disorder is a condition that can provide an indication of Parkinson’s disease well in advance. A research team headed by Professor Dr Erdem Gültekin Tamgüney from Heinrich Heine University Düsseldorf (HHU) has shown that a…
A recent study published in Prion investigated whether trained scent-detection dogs could be used for chronic wasting disease (CWD) surveillance. Study: Canine detection of chronic wasting disease (CWD) in laboratory and field settings. Image Credit: Mechenko/Shutterstock Background CWD is a…
Astrocytes, small star-shaped cells, play an important role in signal transmission in the brain. Since the protein Ezrin is found abundantly in astrocyte tendrils, it is presumed to play a role in brain function. Researchers at the Leibniz Institute on…
