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In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). Study: Extracellular Vesicles, Cell-Penetrating Peptides and…
Each year in the U.S., 5,000 patients receive a diagnosis of ALS, an incurable neurodegenerative disease that will likely kill them within two to five years. In the quest to find a cure for these patients, a team of researchers…
Several studies have indicated that microbial or viral infection could lead to neurodegenerative disease. A recent study published in the journal Neuron has focussed on assessing the putative associations between viral exposures and neurodegenerative disease (NDD) onset, using real-world biobank…
In patients with Huntington’s disease, neurons in a part of the brain called the striatum are among the hardest-hit. Degeneration of these neurons contributes to patients’ loss of motor control, which is one of the major hallmarks of the disease.…
Negative emotions, anxiety and depression are thought to promote the onset of neurodegenerative diseases and dementia. But what is their impact on the brain and can their deleterious effects be limited? Neuroscientists at the University of Geneva (UNIGE) observed the…
A growing pile of evidence indicates that the tens of trillions of microbes that normally live in our intestines -; the so-called gut microbiome -; have far-reaching effects on how our bodies function. Members of this microbial community produce vitamins,…
In elderly adults, the most common neurodegenerative disease is Alzheimer’s disease (AD). It is also the leading cause of dependency and disability. Besides humans, many other animals have been seen to develop certain aspects of AD-like pathology. In a new European…
A perplexing range of neurodegenerative diseases are known to attack distinct regions of the brain, causing severe cognitive and motor deficit. The combined impact of these (generally fatal) diseases has inflicted a devastating toll on society. New insights suggest many…
The reason your three-pound brain doesn’t feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord. This liquid barrier between your brain and skull protects it from…
In this special supplement to the Journal of Parkinson’s Disease, “The Immune System in Parkinson’s Disease,” experts highlight the latest research breakthroughs on the links between immune activation and neuroinflammation and Parkinson’s disease (PD) and discuss the challenges and novel…