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A recent study published in the journal Nature Immunology discovered autoantibodies against chemokines following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The spectrum of coronavirus disease 2019 (COVID-19) manifestation is broad, with convalescent subjects reporting protracted symptoms, a condition…
In cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce the short-term chance of survival, according to a study in the American Journal of Medical Quality. The journal is…
In a recent study posted to the medRxiv* preprint server, researchers used proteomic analysis to identify novel immune cell phenotypes associated with severe coronavirus disease 2019 (COVID-19). Additionally, they compiled cumulative immune cell dysregulation in progressive disease. Study: Proteomic analysis…
In a recent study published in the Immunity journal, researchers explored the current knowledge of the mechanism employed by messenger ribonucleic acid (mRNA) vaccines to elicit innate immune activation. The nucleoside-modified mRNA vaccines used against coronavirus disease 2019 (COVID-19) include…
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the virus responsible for the coronavirus disease 2019 (COVID-19), has infected over 625 million to date and caused over 6.5 million deaths. Although COVID-19 is primarily a respiratory disease, it…
In a recent Nature Reviews Immunology journal study, researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders. Study: Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases. Image Credit: Luca9257 / Shutterstock.com Background Recent research…
As of October 3rd, 2022, the COVID-19 pandemic has led to more than 615 million cases of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), along with over 6.5 million deaths globally, according to the World Health Organization (WHO). Chills, fever,…
Sleep has been long celebrated as the ultimate pick-me-up after a period of excessive labor, stress, illness, or other cause of bodily strain. It affects immunity and inflammatory pathways, thus protecting against cardiovascular disease, neurodegenerative conditions like Alzheimer’s disease and…
Neutrophils, the most abundant type of white blood cell, are the body’s first line of defense against infection. Foreign pathogens can stress the body and activate neutrophils. When activated, neutrophils employ various weapons to protect the body. But if overactivated,…
A team led by Scripps Research scientists has uncovered key details of an immune-cell process that frequently underlies excessive inflammation in the body. The findings could lead to new ways of preventing and/or treating inflammation-related conditions such as sepsis, arthritis,…